Session I: Hepatology, MD – Moderated by David Bernstein

Alcohol associated liver disease and treatment – Nitzan Roth, MD

ALouet A, Thursz M, Kim D, Labreuche J, Atkinson S, Sidhu S, O’Grady J, Akriviadis E, lSinakos E, CarithersJr R, Ramond M, Maddrey R, Morgan T, Duhame A, Mathurin P. Hepatitis, Compared With Pentox. ifylline or Placebo—a Meta-analysis of Individual Data From Controlled Trials https://www.sciencedirect.com/science/article/pii/S0016508518344950#!

Vannier AGL, Shay JES, Fomin V, et al. Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder. JAMA Netw Open. 2022;5(5):e2213014.  doi:10.1001/jamanetworkopen.2022.13014 https://jamanetwork.com/journals/jamanetworkopen/article-abstract/2792500

Warren K, Murray M. Alcoholic liver disease and pancreatitis: Global health problems being addressed by the US National Institute on Alcohol Abuse and Alcoholism 15 July 2013 https://doi.org/10.1111/jgh.12246

Update on liver transplantation – Sanjaya Satapathy, MD

Kwong A J, Kim W R, Lake J R, Smith J M, Schladt D P, Skeans M A, Noreen S M, Foutz J, Booker S E, Cafarella M,  Snyder J J, Israni A K, Kasiske B L. OPTN/SRTR 2019 Annual Data Report: Liver First published: 17 February 2021 https://doi.org/10.1111/ajt.16494

Cholankeril G, Goli K, Rana A, et al. Impact of COVID-19 Pandemic on Liver Transplantation and Alcohol-Associated Liver Disease in the USA. Hepatology. 2021;74(6):3316-3329. doi:10.1002/hep.32067

Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma. Lancet. 2003;362(9399):1907-1917. doi:10.1016/S0140-6736(03)14964-1  https://pubmed.ncbi.nlm.nih.gov/14667750/

Session II: Inflammatory bowel disease – Moderated by Arun Swaminath, MD

Malignancy and IBD: update on the evidence – Keith Sultan, MD

Lo B, Zhao M, Vind I, Burisch J. The Risk of Extraintestinal Cancer in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Cohort Studies. Clin Gastroenterol Hepatol. 2021;19(6):1117-1138.e19. doi:10.1016/j.cgh.2020.08.015

Söderlund, L. Brandt, A. Lapidus, P. Karlén, O. Broström, RobertLöfberg, A. Ekbom, J. Askling. Decreasing Time-Trends of Colorectal Cancer in a Large Cohort of Patients With Inflammatory Bowel Disease https://www.sciencedirect.com/science/article/pii/S0016508509001681

Lutgens, MD, Martijn G. H. van Oijen, PhD, Geert J. M. G. van der Heijden, PhD, Frank P. Vleggaar, MD, PhD, Peter D. Siersema, MD, PhD, Bas Oldenburg, MD, PhD, Declining Risk of Colorectal Cancer in Inflammatory Bowel Disease: An Updated Meta-analysis of Population-based Cohort Studies, Inflammatory Bowel Diseases, Volume 19, Issue 4, 1 April 2013, Pages 789–799,  https://doi.org/10.1097/MIB.0b013e31828029c0

Positioning of IBD therapies: What comes next? – David Rubin, MD

Ponsioen CY, de Groof EJ, Eshuis EJ, et al. Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn’s disease: a randomised controlled, open-label, multicentre trial [published correction appears in Lancet Gastroenterol Hepatol. 2017 Nov;2(11):e7]. Lancet Gastroenterol Hepatol. 2017;2(11):785-792. doi:10.1016/S2468-1253(17)30248-0 https://pubmed.ncbi.nlm.nih.gov/28838644/

Weisshof R, El Jurdi K, Zmeter N, Rubin DT. Emerging Therapies for Inflammatory Bowel Disease. Adv Ther. 2018;35(11):1746-1762. doi:10.1007/s12325-018-0795-9  https://pubmed.ncbi.nlm.nih.gov/30374806/

Ordás I, Mould DR, Feagan BG, Sandborn WJ. Anti-TNF monoclonal antibodies in inflammatory bowel disease: pharmacokinetics-based dosing paradigms. Clin Pharmacol Ther. 2012;91(4):635-646. doi:10.1038/clpt.2011.328  https://pubmed.ncbi.nlm.nih.gov/22357456/

Guide to de-escalation of immune and biologic therapies for IBD – Aline Charabaty, MD

Kennedy NA, Kalla R, Warner B, et al. Thiopurine withdrawal during sustained clinical remission in inflammatory bowel disease: relapse and recapture rates, with predictive factors in 237 patients. Aliment Pharmacol Ther. 2014;40(11-12):1313-1323. doi:10.1111/apt.12980  https://pubmed.ncbi.nlm.nih.gov/25284134/

Turner D, Ricciuto A, Lewis A, et al. STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD. Gastroenterology. 2021;160(5):1570-1583. doi: 10.1053/j.gastro.2020.12.031  https://pubmed.ncbi.nlm.nih.gov/33359090/

Kennedy N, Graham A, Harry A, et al. Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn’s disease: a prospective, multicent re, cohort study https://www.sciencedirect.com/science/article/pii/S2468125319300123?via%3Dihub

Session III: Advanced Endoscopy – Moderated by Juan Carlos Bucobo, MD

Overview and update on the role of POEMS – Petros Benias, MD

Werner, Y. B., Hakanson, B., Martinek, J., Repici, A., von Rahden, B. H., Bredenoord, A. J., … & Rösch, T. (2019). Endoscopic or surgical myotomy in patients with idiopathic achalasia. New England journal of medicine, 381(23), 2219-2229.  https://www.nejm.org/doi/full/10.1056/NEJMoa1905380

Rubin D T,  Ananthakrishnan F A, Ashwin N. et al. Clinical Guideline: Ulcerative Colitis in Adults, The American Journal of Gastroenterology: March 2019 – Volume 114 – Issue 3 – p 384-413 doi: 10.14309/ajg.0000000000000152  https://journals.lww.com/ajg/fulltext/2019/03000/acg_clinical_guideline__ulcerative_colitis_in.10.aspx

Schett G, McInnes IB, Neurath MF. Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs. N Engl J Med. 2021;385(7):628-639. doi:10.1056/NEJMra1909094  https://pubmed.ncbi.nlm.nih.gov/34379924/

Endoscopic therapy for Barrett’s esophagus – Arvind Trindade, MD

Qumseya B, Sultan S, et al. ASGE STANDARDS OF PRACTICE COMMITTEE, ASGE guideline on screening and surveillance of Barrett’s esophagus. Gastrointest Endosc. 2019;90(3):335-359.e2. doi:10.1016/j.gie.2019.05.012 https://pubmed.ncbi.nlm.nih.gov/31439127/

Orman ES, Li N, Shaheen NJ. Efficacy and durability of radiofrequency ablation for Barrett’s Esophagus: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2013;11(10):1245-1255. doi:10.1016/j.cgh.2013.03.039  https://pubmed.ncbi.nlm.nih.gov/23644385/

Pohl H, Welch H G, The Role of Overdiagnosis and Reclassification in the Marked Increase of Esophageal Adenocarcinoma Incidence, JNCI: Journal of the National Cancer Institute, Volume 97, Issue 2, 19 January 2005, Pages 142–146, https://doi.org/10.1093/jnci/dji024

Pancreatic cyst evaluation and management – Kara Raphael, MD

Maurice W. M. D. Lutgens, MD, Martijn G. H. van Oijen, PhD, Geert J. M. G. van der Heijden, PhD, Frank P. Vleggaar, MD, PhD, Peter D. Siersema, MD, PhD, Bas Oldenburg, MD, PhD, Declining Risk of Colorectal Cancer in Inflammatory Bowel Disease: An Updated Meta-analysis of Population-based Cohort Studies, Inflammatory Bowel Diseases, Volume 19, Issue 4, 1 April 2013, Pages 789–799, https://doi.org/10.1097/MIB.0b013e31828029c0

Lu MJ, Qiu XY, Mao XQ, Li XT, Zhang HJ. Systematic review with meta-analysis: thiopurines decrease the risk of colorectal neoplasia in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2018;47(3):318-331. doi:10.1111/apt.14436  https://pubmed.ncbi.nlm.nih.gov/29205426/

Meserve J, Facciorusso A, Holmer AK, Annese V, Sandborn WJ, Singh S. Systematic review with meta-analysis: safety and tolerability of immune checkpoint inhibitors in patients with pre-existing inflammatory bowel diseases. Aliment Pharmacol Ther. 2021;53(3):374-382. doi:10.1111/apt.16217  https://pubmed.ncbi.nlm.nih.gov/33314269/

Diversity, equity and inclusion in gastroenterology – Amrita Sethi, MD

Kamani L, Pausawasdi N, Hooft JEV, Sethi A, Sachithanandan S. Redesigning the Landscape for Women and Leadership: Insights Gained from the Covid-19 Pandemic. On Behalf of Women in Gastroenterology Network Asia Pacific (WIGNAP) and Women in Endoscopy (WIE). Clin Endosc. 2020 Sep;53(5):620-622. doi: 10.5946/ce.2020.202. Epub 2020 Sep 29. PMID: 33027586; PMCID: PMC7548141.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548141/

Rabinow itz LG, Anandasabapathy S, Sethi A, Siddiqui UD, Wallace MB, Kim MK. Addressing gender in gastroenterology: opportunities for change. Gastrointest Endosc. 2020;91(1):155-161. doi:10.1016/j.gie.2019.08.039  https://pubmed.ncbi.nlm.nih.gov/31499044/

Siddiqui UD, van Hooft JE, Sethi A. Gender disparities in advanced endoscopy fellowship: Women in Endoscopy (WIE) perspective. Endosc Int Open. 2021;9(4):E505-E506. doi:10.1055/a-1339-1432 https://pubmed.ncbi.nlm.nih.gov/33816769/

Session IV: General GI/IBS – Moderated by Bethany Devito, MD

Updated colon cancer screening and surveillance guidelines – Joseph Anderson, MD

Promrat K, David E. KleinerH M, Niemeier E, Jackvony M, Kearns J R, Wands J L, Fava R. Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis† First published: 23 December 2009 https://doi.org/10.1002/hep.23276

Romero-Gómez M, Zelber-Sagi S, Trenell M. Treatment of NAFLD with diet, physical activity and exercise. J Hepatol. 2017;67(4):829-846. doi:10.1016/j.jhep.2017.05.016

Colombo, M, Pelusi, S.Towards Precision Medicine in Nonalcoholic Fatty Liver Disease with PNPLA3 as a Therapeutic Target  Published: August 07, 2019DOI:https://doi.org/10.1053/j.gastro.2019.08.003  https://www.gastrojournal.org/article/S0016-5085(19)41190-6/fulltext

Clostridium difficle: Updates on diagnosis and management – Calley Levine, MD

L Cl Kelly CR, Fischer M, Allegretti JR, et al. ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections [published correction appears in Am J Gastroenterol. 2022 Feb 1;117(2):358]. Am J Gastroenterol. 2021;116(6):1124-1147. doi:10.14309/ajg.0000000000001278  https://pubmed.ncbi.nlm.nih.gov/34003176/

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clinical Infectious Diseases, Volume 66, Issue 7, 1 April 2018, Pages e1–e48, https://doi.org/10.1093/cid/cix1085

Tariq R, Singh S, Gupta A, Pardi DS, Khanna S. Association of Gastric Acid Suppression With Recurrent Clostridium difficile Infection: A Systematic Review and Meta-analysis. JAMA Intern Med. 2017;177(6):784–791. doi:10.1001/jamainternmed.2017.   https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2612117

Session V: Motility – Moderated by Mary Cheung, MD

Achalasia: evaluation and management update – Christopher Vélez, MD

Pandolfino JE, de Ruigh A, Nicodème F, Xiao Y, Boris L, Kahrilas PJ. Distensibility of the esophagogastric junction assessed with the functional lumen imaging probe (FLIP™) in achalasia patients. Neurogastroenterol Motil. 2013;25(6):496-501. doi:10.1111/nmo.12097    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789137/

Chronic constipation: advanced diagnostics and therapeutics – Sara Cerrone, MD

Lacy, B., et al. ACG Clinical Guideline: Management of IBS. Am J Gastroenterol 2021;116:17-44. https://pubmed.ncbi.nlm.nih.gov/33315591/

Paquette IM, Varma M, Ternent C, et al. The American Society of Colon and Rectal Surgeons’ Clinical Practice Guideline for the Evaluation and Management of Constipation. Dis Colon Rectum. 2016;59(6):479-492. doi:10.1097/DCR.0000000000000599 https://pubmed.ncbi.nlm.nih.gov/27145304/

ASGE Standards of Practice Committee, Cash BD, Acosta RD, et al. The role of endoscopy in the management of constipation. Gastrointest Endosc. 2014;80(4):563-565. doi:10.1016/j.gie.2014.06.018  https://pubmed.ncbi.nlm.nih.gov/25150599/

Main Session – Advanced Endoscopy “Cool” Cases

Sumant Inamdar, MD, Peter Stein, MD, Calvin Lee, MD, Larry Miller, MD

Ong, John MSc*; Swift, Carla MRCP†; Stokell, Benjamin G. MMath‡; Ong, Sharon MMed§; Lucarelli, Pierino FRCS∥; Shankar, Arun FRCP¶; Rouhani, Foad J. FRCS#,**; Al-Naeeb, Yasseen FRCP†† Bouveret Syndrome, Journal of Clinical Gastroenterology: October 2020 – Volume 54 – Issue 9 – p 758-768 doi: 10.1097/MCG.0000000000001221 https://journals.lww.com/jcge/toc/2020/10000

Session I: Health care maintenance in IBD – Sheelamma Thomas, NP

Ananthakrishnan AN, Nguyen GC, Bernstein CN. AGA Clinical Practice Update on Management of Inflammatory Bowel Disease in Elderly Patients: Expert Review. Gastroenterology. 2021;160(1):445-451. doi:10.1053/j.gastro.2020.08.060 https://pubmed.ncbi.nlm.nih.gov/33011177/

Hashash JG, Picco MF, Farraye FA. Health Maintenance for Adult Patients with Inflammatory Bowel Disease. Curr Treat Options Gastroenterol. 2021;19(4):583-596. doi: 10.1007/s11938-021-00364-9. Epub 2021 Nov 22. PMID: 34840495; PMCID: PMC8608358. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608358/

Shrestha MP, Ruel J, Taleban S. Healthcare maintenance in elderly patients with inflammatory bowel disease. Ann Gastroenterol. 2017;30(3):273-286. doi:10.20524/aog.2017.0130 https://pubmed.ncbi.nlm.nih.gov/28469357/

Session III: Clinical updates in the management of Liver Disease – Maly Tiev, NP

Redman, J., Sterling, R.K. Non-invasive Assessment of Liver Fibrosis. Curr Treat Options Gastro 18, 255–269 (2020). https://doi.org/10.1007/s11938-020-00285-z

Norah A. Terrault,Anna S.F. Lok,Brian J. McMahon,Kyong-Mi Chang,Jessica P. Hwang,Maureen M. Jonas,Robert S. Brown Jr.,Natalie H. Bzowej,John B. Wong. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance
First published: 05 February 2018 https://doi.org/10.1002/hep.29800